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Imaging studies revealed diminished activation in brain regions such as the insula, putamen, and orbitofrontal cortex when exposed to high-calorie food cues, suggesting that GLP1-S reshapes both physiological hunger responses and the motivational aspects of eating

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Eating disorder treatment is about building a healthier and better relationship with food, Ihlenfeld said

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In the SURMOUNT-1 trial, tirzepatide users saw a 10.9% lean mass reduction over 72 weeks, while approximately 74% of total body weight lost came from fat mass