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Brain: appetite suppression In the brain, GLP-1 RAs act on the hypothalamus, which is involved in appetite regulation, to give a feeling of satiety and reduce appetite [5]

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Some individuals unconsciously increase portion sizes during meals when they do experience hunger, or they may consume calorie-dense beverages that do not trigger the same satiety signals as solid foods

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The frustrating but honest answer is that it varies considerably from person to person

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