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Fcy::Fur fusion catalyzes transformation processes wherein five-fluorocytosine (5-FC) is converted selectively, yielding toxic derivatives known as five-fluorouracil (5-FU), effectively targeting only malignant cellular populations without adversely affecting surrounding healthy tissue structures ( Recently, Kazuhides team successfully integrated killer red (KR) gene allowing light-induced singlet oxygen generation, which markedly enhanced overall effectiveness regarding treatments administered under laser irradiation particularly noted among cases involving both gliobastomatosis multiple myelomas ( To enhance safety profiles related specifically toward employing HSV-1-based therapeutics aimed at combating cancers, certain critical genomic deletions occur preventing uncontrolled propagation/infection events

In hens, PA treatment significantly alleviated the inhibition of ovarian somatic cell proliferation and decreased cell apoptosis in D-gal-induced and natural aging ovarian tissues by reducing oxidative stress (Liu X et al., 2018)

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Opala G, Winter S, Vance C, et al

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