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The prescribing information includes warnings about acute kidney injury, particularly in patients experiencing volume depletion
Theres more research to be done, Cork says
The compound is currently in Phase 3 evaluation under the TRIUMPH program, which spans registrational trials in obesity, obstructive sleep apnea, and knee osteoarthritis (PMID 41090431)
These medications affect brain reward pathways that process food pleasure and cause delayed gastric emptying, which can create food aversions and alter taste perception
Ranke MB, Savage MO, Chatelain PG, Preece MA, Rosenfeld RG, Wilton P
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