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Costs per user would decline over time, from $5,600 per person in 2026 to $4,300 per person in 2034, but are likely to be offset by increased uptake

What is also unknown is the effect on cognition, and any neuroprotective benefit, in younger or healthy individuals remains unknown, some positive results have been reported, 6 however a large scale confirmatory study is still required

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The skill gap between SubQ and IM is real, and it shows up in compliance data

For clinical translation, assays with standardized pipelines, interpretable outputs (risk scores or endotypes linked to interventions), and external validation are more likely to be adopted than discovery-oriented atlases that lack feasible clinical implementations [93]

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