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Weight loss at 80 weeks (efficacy estimand): Cardiometabolic risk factors at 80 weeks (12 mg): triglycerides -37.0% , hsCRP -51.2% , non-HDL cholesterol -16.5% , systolic blood pressure -9.3 mmHg , waist circumference -7.5 in (19.0 cm)

If youve been looking into ways to manage your weight, chances are youve heard about semaglutide

Author CB received lecture fees and served as a consultant for Takeda, MSD, Ferring, Abbvie, Galapagos and Janssen

If you dont continue to use your prescription as directed, it will not continue to treat your type 2 diabetes or weight-related medical problems, both of which are chronic conditions

Direct answer: Semaglutide is generally safe long-term, but patients should expect ongoing digestive effects and require routine monitoring

Q6: Can it be combined with other longevity therapies