For a 2mg vial, 2mL of bacteriostatic water creates a 1mg/mL concentration
16,51,52 Herniated discs trigger an innate and adaptive immune response with infiltration of macrophages, T and B cells, and the up-regulation of a myriad of pro-inflammatory cytokines, e.g., IL-1, IL-6, IL-8, IL-10, IL-17, IFN-, CCL2, TNF- and PGE2
& Sadok, S
PDK4, Pyruvate Dehydrogenase Kinase 4
What may improve includes: Pain intensity and frequency Radiating symptoms (sciatica) Morning stiffness and mobility Tolerance for sitting, standing, and daily activities Sleep quality affected by pain Dependence on pain medications Many users with disc herniations report 50% to 80% improvement in symptoms while their imaging findings remain unchanged
Allergy can also be an important treatment, and desensitization in many is important