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PPI mesh topology analysis A PPI network diagram for the three overlapping HT genes was created using the STRING database, the ferroptosis-related genes and CRC targets (the threshold for interaction score was set at 0.4.), as shown in Fig

There is a significant age-dependent increase in ferroptosis in the kidney, spleen, liver, ovary, uterus, cerebellum, and bone marrow, accompanied by iron accumulation 41

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When the herniated material compresses a nerve root, patients typically experience radiating pain (sciatica), numbness, tingling, or muscle weakness in the leg or foot served by that nerve

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