Eli Lilly has applied for licensing in more than 40 countries for both type 2 diabetes and weight management, with plans for a rapid launch if its approved
The mechanism is sound and the pharmacology is well characterized
Abstract Glucagon-like peptide-1 medicines are being prescribed to growing numbers of patients worldwide, for type 2 diabetes, obesity and associated comorbidities, including cardiovascular disease, peripheral artery disease and obstructive sleep apnea, and are revolutionizing public health strategies for these conditions
PMID: 9156038
In 2022, Enbrel contributed about $4.12 billion to Amgens sales
Beyond these regions, relevant GLP-1 receptor populations have been identified in at least 10 additional brain areas, pointing to physiological roles that extend well beyond feeding