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Unlike synthetic human growth hormone, these peptides do not replace your natural hormones
Does that kind of make sense
The blood flow to bones is vital for skeletal health, and GLP-1RAs may improve it, while the precise processes are not entirely known
That said, this combination should always be coordinated with your rheumatologist
The mechanism of action of GLP-1 agonists involves binding to GLP-1 receptors on pancreatic beta cells, which stimulates glucose-dependent insulin secretion
its additional glucagon receptor activity may further complicate GI effects, though this is not yet fully established
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