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The synergy isn't additiveit's multiplicative, provided dosing timing prevents competitive inhibition at the cellular level

To evaluate the FOXO4 FHD-binding region in p53 TAD using a dynamic tool, we attempted to measure the hetNOE of the apo- and FHD-bound states of p53 TAD

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Dose- and time-dependent effects were also identified: the group that received 15 mL of ACV had the largest reduction, whereas the most significant changes occurred at 12 weeks