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Research suggests it acts through modulation of several interconnected signaling pathways simultaneously a broad mechanism of action that helps explain its observed multisystemic effects in laboratory models, and that also makes it challenging to evaluate through conventional single-target drug development frameworks
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10.1088/1361-6463/ac2530 82 RizosE.BairaktariE.KostoulaA.HasiotisG.AchimastosA.GanotakisE.et al (2003)
however, dulaglutide had a neutral effect on HF hospitalisation
Around 30% of patients start with bulbar symptoms, which affect the muscles used for speaking and swallowing, leading to problems like slurred speech (dysarthria), trouble swallowing (dysphagia), and twitching of the tongue muscles (Chi et al., 2013)
v) clear measures for intervention and control
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