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Flanagan JL, Simmons PA, Vehige J, Willcox MD, Garrett Q

The results of this trial were quite interesting and have been published internationally, plasma thiamine levels of both thiamine and placebo groups were significantly depleted as compared to normal controls

Here is the complete dosage chart for 5mg/mL concentration: Some people need doses between these standard steps

But we don't stop there

But it does mean that side effects during the first week or two of a dose increase are not necessarily representative of what that dose feels like at steady state