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Anti-Inflammatory Properties Chronic inflammation accelerates aging, heart disease, and cognitive decline
doi: 10.3892/mmr.2019.10297 112 LiN.WangW.ZhouH.WuQ.DuanM.LiuC.et al
Physiology, obesity, neurohormonal appetite, and satiety control
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For instance, PAGln significantly alleviates doxorubicin-induced cardiac toxicity via gut microbial metabolism regulation, reverses abnormal myocardial gene expression (e.g., Klb, Ece2, Casq1), and mitigates myocardial injury and apoptosis through mechanisms involving lipid metabolism, calcium signaling pathways, and store-operated Ca 2+ channel activity (Huang et al., 2025)
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