glp-1 lasker glp 1 discovery The transformative breakthroughs in research recognized by the 2024 Lasker~DeBakey award Lasker Award Winner: GLP-1 Drugs

For patients whose prior B12 supplementation hasn't worked, injection is the solution not a higher oral dose

The combined hepatic effects of these agents have not been studied

Nikolaidis LA, Elahi D, Hentosz T, Doverspike A, Huerbin R, Zourelias L, Stolarski C, Shen YT, Shannon RP: Recombinant glucagon-like peptide-1 increases myocardial glucose uptake and improves left ventricular performance in conscious dogs with pacing-induced dilated cardiomyopathy

Surgical Interventions and Headache Surgical intervention is typically reserved for individuals with BMI 40 or with BMI 35 with related health issues (BMI 30 is also sometimes accepted)

The same mechanism plays a role in how the body feels hunger, which is why the drugs are valuable in weight loss

But thats just one small study so far