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If a dose increase causes intolerable GI symptoms, the Phase 2 protocol explicitly permitted returning to the prior dose level and waiting a full 4 weeks before re-attempting escalation

Found will ask about your health history, including what you have tried and what has and hasn't worked you, as well as what's realistic in your current schedule

Mean weight reductions were: 15 mg dose: 20.9 percent 10 mg dose: 19.5 percent 5 mg dose: 15.0 percent Placebo: 3.1 percent At the highest dose, 57 percent of participants lost at least 20 percent of their body weight, and 36 percent lost at least 25 percent [2]

GPOs increasingly include supply reliability metrics in biosimilar contracting criteria alongside price

Garber A, Henry RR, Ratner R, Hale P, Chang CT, Bode B, et al

Dec 2006;77(7-8):568-573