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Gestational weight gain and pregnancy outcomes after GLP-1 receptor agonist discontinuation
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Semaglutide (SEM) is a recently introduced GLP-1 receptor agonist (GLP-1RA) for the treatment of obesity and type 2 diabetes mellitus by mitigating insulin resistance
Lab values showing elevated hemoglobin A1c
Activation triggers a Gq-linked cascade: phospholipase C is stimulated, IP3 mediates calcium release from intracellular stores, and the resulting calcium influx drives exocytosis of stored growth hormone granules into circulation
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