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Improve access to advanced therapies

IARC (1993) Ochratoxin A

Because each of the major studies for SGLT2is, GLP1-RAs, and nsMRAs added these newer therapies to participants on the maximum label or tolerated dose of an angiotensin-converting enzyme inhibitor (ACEi) or angiotensin receptor blocker (ARB), it is suggested that cardiorenal protective therapy begin with either an ACEi or an ARB, titrated to either the label maximum or the maximum tolerated dose (see Table 1 for list of currently approved ACEi and ARB in Canada and the maximally recommended dosing)

Strengths and Substitutes Extensior 1 mg Injection is available as a prefilled multi-dose pen in various strengths

But the people in the injection study began with a higher A1c, and higher starting A1c levels usually allow for a larger reduction

GLP-1 medications should be avoided during pregnancy and breastfeeding