Semaglutide works by mimicking the effects of GLP-1 (glucagon-like peptide 1), a hormone that helps regulate blood sugar, reduces appetite, and slows down the emptying of the stomach
GLP-1 drugs, especially injectable versions, can sometimes cause local irritation at the injection site, such as skin discoloration or swelling
With Ozempic, this is in the range of 15-20% of body weight, and this is likely even higher for Mounjaro
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