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Not only does NAC alone not appear to help muscle protein synthesis or nitric oxide metabolism like Setria Performance Blend was hoped to, some studies also suggest that NAC may inhibit the body's nitric oxide production by interfering with the absorption of nitrite in the kidneys

2025;15(1):35188.[DOI] 109

The combination also carries potential legal and regulatory issues, as Ipamorelin is often used for research purposes and may not be approved for medical use