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baumannii , a gene cluster for the metabolism of L-carnitine under aerobic conditions was predicted and bacterial growth on L-carnitine as the sole carbon and energy source was demonstrated ( lysR ), the energy-dependent import system BCCT and the two-component carnitine monooxygenase which catalyzes the oxygen-dependent cleavage of L-carnitine into TMA and MSA ( in vivo and in vitro reconstitution experiments clearly demonstrated the conversion of L-carnitine via MSA and D-malate to pyruvate, CO 2 and TMA

Under basal conditions, KEAP1 sequesters NRF2 within a complex with Cullin 3 (CUL3), which is an ubiquitin ligase E3 that targets NRF2 for proteosomal degradation (Kobayashi et al., 2004)

3d) indicating good protection in comparison to SUN alone (Fig

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Carcinogenesis 18 , 641644 (1997)