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While these conventional treatments may produce faster initial results, they often come with significant drawbacks including skin irritation, photosensitivity, and potential rebound hyperpigmentation upon discontinuation

[9] [10] The authoritative sources for retatrutide storage are the IMP label or carton, the sponsor's Pharmacy Manual, and the instructions of the trial site pharmacist

Since then, the precise molecular targets and the sequencing and combinations of ADT drugs used have evolved considerably, as has our knowledge of the structural basis that underlies the effectiveness of or resistance to ADT [4]

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Subgroup analyses were performed for several pre-specified factors, including age, sex, race/ethnicity, and T2D, among others

The authors said future research will explore how patient characteristics, specific medications, and timing of therapy influence treatment trajectories, with the goal of informing more personalized and sustainable approaches to obesity care