These changes to normal gastrointestinal physiology explain why diarrhea (defined as three or more loose or watery stools per day) and other gastrointestinal symptomsincluding nausea, vomiting, constipation, and abdominal painare among the most frequently reported side effects
If you have heart or kidney disease, speak with your healthcare provider about appropriate fluid intake
(More information) Vitamin E deficiency can be caused by fat malabsorption disorders or by genetic abnormalities that affect vitamin E transport
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Certain features warrant prompt medical evaluation: Severe muscle pain or weakness , particularly if accompanied by dark urine, which may indicate rhabdomyolysis (a rare but serious condition involving muscle breakdown) Joint swelling, redness, or warmth , which could suggest inflammatory arthritis or infection (septic arthritis) Pain that significantly impairs daily activities or does not respond to simple analgesia Systemic symptoms such as fever, unexplained weight loss (beyond expected therapeutic effect), or night sweats New or worsening pain following dose escalation, which may require dose adjustment or further investigation Sudden, severe pain in the right upper abdomen , possibly with fever or jaundice, which could indicate gallbladder disease (a recognised risk with GLP-1 receptor agonists) [1] [5] Patients should also seek advice if they experience other concerning adverse effects of Ozempic, including: Persistent nausea or vomiting leading to dehydration or reduced fluid intake Symptoms of hypoglycaemia (tremor, sweating, confusion), particularly if taking Ozempic with insulin or sulphonylureas Severe abdominal pain, which may indicate pancreatitis (a known but uncommon risk with GLP-1 receptor agonists) [1] [5] Visual changes or signs of diabetic retinopathy progression For urgent concerns outside of GP hours, patients should contact NHS 111

Hair loss is not a listed side effect of GLP1 drugs, but rapid weight loss from any method can disrupt hair growth cycles