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Psychopharmacology 168:262270 Ray A (2023) Retatrutide: a triple incretin receptor agonist for obesity management

But the rationale is sound: GLP-1 receptors exist on a continuum of activation, and partial activation may produce partial benefits with fewer side effects

It softens stools, making them easier to pass and lowering the risk of constipation

All this potential can easily come crumbling down, as demonstrated by Pfizers disappointing Phase 2b results late last year

Accessed August 2024 at Hurtado MD, Tama E, Fansa S, et al

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