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But how do they work, and why are they being considered for Lyme disease

9. Stout JR et al. Exp Gerontol. 2015;64:33-34. 10. Deutz et al. Clin Nutr. 2013;32(5):704-712

Kidney or liver issues : Dose adjustments or avoidance if severe, as the drugs are processed through these organs

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CaMKK2 dysfunction may play an underlying role in this phenomenon as genetic deletion of Camkk2 in hippocampal neurons, myeloid cells and immortalized cell lines (HEK293 and HepG2) results in mitochondrial dysfunction that causes a similar switch in cellular energy generation from oxidative phosphorylation to glycolysis [43, 201, 202]