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Inject subcutaneously at a clean, rotated site abdomen, thigh, or upper arm For how to manage any side effects during titration, see our [semaglutide side effects guide](/guides/semaglutide-side-effects-how-to-manage)

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Those antibodies could make future doses less effective, increase the risk of future reactions, or, in some therapeutic proteins, interfere with related natural proteins in the body

And if you're skinny fat, you know exactly what I'm talking about, you're not overweight

It focuses on fat reduction

Find out if you should be concerned in our article: Is it safe to drink coffee regularly