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Interestingly, the ROS level also increased during MuSC activation (Supplementary Fig

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Pawel MK, Kamachi T, Kumar M, Yoshizawa K

Individuals with MASH usually are asymptomatic in the early stages or present symptoms that are not closely related to the disease, leading to delayed diagnoses and treatment

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Activation of the GLP-1 receptor is known to improve endothelial function and reduce arterial inflammation, while glucagon receptor agonism enhances lipid metabolism and fat oxidation, directly combating atherosclerosis and reducing visceral adiposity