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The pipeline of next-generation treatments is advancing rapidly: Novo Nordisks CagriSema, a fixed-dose combination of semaglutide and the amylin analogue cagrilintide, has an FDA decision expected in late 2026 and could further accelerate the market

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After a month-long break, a conservative approach often involves restarting at a lower dosetypically the starting dose of 2.5 mg weekly or one step below the previous maintenance dosethen re-escalating according to the standard titration schedule

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