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Glutathione depletion induced by c-Myc downregulation triggers apoptosis on treatment with alkylating agents

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PubMed Malinda, K.M., Sidhu, G.S., Mani, H., Banaudha, K., Maheshwari, R.K., Goldstein, A.L., & Kleinman, H.K

In order to determine if compounds showed selective inhibition of TGR compared to human TrxR and GR, the IC 50 values for TGR were compared to those of human TrxR and GR either reported in literature or determined here (Table 4)

doi: 10.1016/j.ijantimicag.2020.106054 257 ShyerJ