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subcutaneous produces reliable systemic absorption Requires greater technique and carries a marginally higher risk of injection site reaction Who injection is best suited for: Tendon, ligament, or muscle injuries Post-surgical tissue recovery Bone healing support Systemic anti-inflammatory goals Any indication where the target tissue is not the GI tract Practical considerations: Requires comfort with self-injection or clinical administration Sterile preparation is non-negotiable contaminated peptide solutions carry real infection risk Quality of the compound matters enormously

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Radiat Res 122:8694 Han P, Clingen PH, Lowe JE, Katsuya A, Arlett CF, Green MHL (1998) Repair of cyclobutane pyrimidine dimers in unstimulated human mononuclear cells is deficient at very low fluencies of ultraviolet B and is not enhanced by addition of deoxyribonucleosides

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