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Carnesecchi J, Malbouyres M, de Mets R, et al

Kidney Disease: Individuals with significant renal impairment require medical evaluation before initiating injectable glutathione, as the kidneys play important roles in glutathione metabolism and excretion of glutathione conjugates

Presence of 2 mM meso -tartrate in the standard MDH activity assay (containing 2 mM D-malate) revealed a significant reduction of the enzyme activity (0.93 0.1 mol min 1 mg 1 )