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Individuals on a GLP-1 receptor drug reported the following: 65% reported nausea, compared to 16% of placebo 37% reported abdominal pain, compared to 6% of placebo
Overall, whilst these findings imply that increased production of ROS is associated with C9orf72-ALS, it is unclear whether loss of C9orf72 or expression of hexanucleotide repeat expansions disturbs redox homeostasis
Glucagon-like peptide-1 (7-36) amide: a central regulator of satiety and interoceptive stress
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Malerba M, Clini E, Cremona G, et al
PMOS is an endocrine disorder with broader metabolic manifestations, which can include obesity, insulin resistance, acne, hirsutism, and elevated long-term risk of diabetes and cardiovascular disease
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