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5 NADPH/NADP + Equilibrium and its Impact on ACE2 5.1 NADPH Oxidase Promotes Oxidative Stress NADPH oxidase is a membrane-bound enzymatic complex that reduces O 2 to superoxide and is primarily found in phagocytotic cells, endothelial cells, vascular smooth muscle cells, and cardiac myocytes [53]

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Patients experiencing persistent metallic, bitter, or otherwise altered taste should consider these contributing factors and discuss them with their healthcare provider