Supplementation of vitamin 12 in amounts up to 1000 mcg can be consumed safely
Key Takeaway B12 injections can help relieve neuropathy symptoms and support nerve repair, especially when deficiency is present
RAB29 is also a risk gene of PD identified in PARK16 loci from several GWASs (Satake et al., 2009), and in addition to mitochondria Rab29 is also distributed at trans-Golgi network, lysosomes, and autophagic vesicles to regulate membrane trafficking, lysosome homeostasis, and axonal transport of autophagosomes with LRRK2 (Eguchi et al., 2018
Most of these effects appear to outperform placebo
The diluent type and volume are specified by the product's SmPC
Healthcare providers will usually do blood tests to check for B12 deficiency in people who have a high risk of developing it