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the index date for the comparison group was randomly chosen among weighted dates of SGLT2i prescriptions for each individual to match the distribution of time from the first observed SGLT2i prescription to the index date in the combination group

doi: 10.1038/s41598-021-97440-y 70 ShiimuraY.HoritaS.HamamotoA.AsadaH.HirataK.TanakaM.et al

But patients without neuropathy saw their transit time jump from about 1 hour to 2.5 hours [19]

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