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Les personnes de 40 ans et plus sont les premires concernes : les niveaux de glutathion diminuent naturellement avec l'ge, ce qui rduit la capacit de l'organisme neutraliser les radicaux libres et se protger du vieillissement cellulaire
doi:10.3760/cma.j.issn.1009-2587.2019.08.014
High stress, infections, antacids, and other medications deplete intrinsic factors
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In fact, the use of GSTP1 knockout mice demonstrated that loss of GSTP1 expression increases sensitivity to metabolic or environmental toxins and promotes mutations and cancer development ( FIGURE 2 Prostate cancer Promoter hypermethylation leading to epigenetic silencing of GSTP1 gene expression is frequently detected in prostate cancer cells, the most commonly diagnosed type of malignancy among men in Western European countries and the second cause of cancer-related deaths among men worldwide (Jeronimo et al., 2002
Science 381 , eadd6696 (2023)
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