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Mean weight reduction reached 20.1% in participants without type 2 diabetes, with continuous weight loss through the study endpoint suggesting further potential with longer treatment duration

This is particularly important because lentigo maligna melanoma has high recurrence rates (likelihood of the cancer returning), with up to 20 percent of cases returning after treatment

It counteracts muscle atrophy and promotes full functional recovery, as evidenced by improved biomechanical and functional assessments in treated rats

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The following guidance is based on best practice for subcutaneous injectable therapies and should be adapted in line with any specific instructions provided in the retatrutide product PIL once licensed