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Elevated serum B12 levels (hypercobalaminaemia) detected on blood tests may indicate underlying conditions such as liver disease, kidney dysfunction, or myeloproliferative disorders rather than representing a direct cause of symptoms

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Furthermore, L-SOD could also reduce OxS to intestinal barrier, thereby ameliorating the vicious circle between hyperglycemia and the oxidative damage 751

ELISA assays complement the HPLC analysis by measuring concentrations of melatonin and neurotrophic factors, utilizing kits from Sangon Biotechnology Company (Shanghai, China) following strict protocols to ensure reliability

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