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Massons trichrome staining additionally indicated that PQQ-treatment protected against TAC-induced myocardial fibrosis in these animals (Figure 1I)

Patients near goal weight are often looking for a lower, steady dose rather than continued escalation, and do not see why they would need the full treatment dose forever

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Guidelines have evolved considerably from routine medication cessation in 2023 to GLP-1 RA continuation with individualised risk assessment in 20242025, illustrating increasing acknowledgment that certain theoretical risks may be underestimated

Corrales RM, Luo L, Chang EY, Pflugfelder SC: Effects of osmoprotectants on hyperosmolar stress in cultured human corneal epithelial cells