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Examination of electron transport chain function in muscle and fibroblast culture, histological and electron microscopy examination of muscle and other biomarkers of mitochondrial metabolism revealed a pattern consistent with the notion that PPA could be interfering with mitochondrial metabolism at the level of the tricarboxylic-acid cycle (TCAC)

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These improvements are often seen alongside, and partly as a result of, sustained weight loss

The serum LC and ALC concentrations of all the individuals in the HC and MDD groups were compared with an independent-sample t -test and the serum LC and ALC concentrations of MDD before and after treatment were compared with a paired-sample t -test

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