The non-essential amino acid cysteine becomes essential for tumor proliferation and survival
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However, the largest Phase IIb trial involving 536 subjects failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading Metabolic Pharmaceuticals to terminate development in 2007
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doi: 10.1002/jlb.3ma1217-502r 105 YangMHWuFXXieCMQingYFWangGRGuoXLet al