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When cagrilintide activates them, appetite drops and the sensation of fullness lasts longer between meals

The receptor reduces ghrelin: hormones that make you feel hungry and increases the release of GLP-1

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For example, (1) Glucagon-like peptide 1 (GLP1) is an intestinal hormone that can enhance insulin secretion in a glucose-dependent manner by activating the GLP-1 receptor (GLP-1R) that is highly expressed on islet cells