Herbal and natural supplements further complement the market, providing plant-based or alternative options
As shown in Figure 7, since the filing of the main compound patents in 2006, Novo Nordisk has been applying for patents consistently over a period of 17 years, with heavier patenting activity in 2019, two years before Wegovy was approved
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But the evidence shows: Pancreatitis is rare Most cases are not caused by GLP-1s Gallstones and rapid weight loss are more likely culprits The benefits of GLP-1 therapy for obesity and diabetes are significant With proper supervision, GLP-1 medications remain safe and effective tools in managing chronic metabolic disease.
Overall, the adverse events reported were similar to those expected with the GLP1-R agonist class of drugs
The FDA approved Zepbound (tirzepatide for obesity) on November 8, 2023 [2], meaning it entered the obesity-specific reimbursement field only recently