To avoid deficiencies: Focus on nutrient-dense meals , not just calorie reduction Prioritize lean proteins , eggs , leafy greens , nuts/seeds , legumes , and whole grains Consider registered dietitian support if appetite remains low for prolonged periods Hair loss from GLP-1 medications like semaglutide or tirzepatide is rarely permanent
Crucially, certain miRNAs exhibit aberrant expression patterns in the brain tissues and biofluids of PD patients or models, highlighting their potential as minimally invasive diagnostic or prognostic biomarkers
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GLP-1 receptor agonists slow gastric emptying and suppress appetite, which can reduce energy intake and cause fatigue Fatigue is most common during initial weeks and dose increases, often improving as the body adapts over several weeks to months Nutritional deficiencies in protein, iron, vitamin D, and B vitamins may develop when food intake drops significantly Optimising nutrition with nutrient-dense foods, maintaining hydration, and gentle physical activity can significantly reduce tiredness Contact your GP if fatigue is severe, worsening, or accompanied by signs of dehydration, hypoglycaemia, or persistent gastrointestinal symptoms Table of Contents Why GLP-1 Medications Can Cause Tiredness Glucagon-like peptide-1 (GLP-1) receptor agonists are increasingly prescribed medications for type 2 diabetes and weight management, including semaglutide (Ozempic, Wegovy) and liraglutide (Victoza, Saxenda)

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