The present review aims to fill this gap of knowledge by evaluating the existing evidence on muscle wasting associated with GLP-1RAs use and by exploring prevention strategies and treatment approaches to maintain muscle mass and function during GLP-1RAs therapy
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These effects explain why medications targeting the GLP-1 pathway have proven effective for both type 2 diabetes management and weight loss
Regarding skin preparation, if the injection site is visibly dirty, cleaning with soap and water or an alcohol wipe is recommended
Participants received tirzepatide at 5 mg, 10 mg, or 15 mg, or placebo, via weekly subcutaneous injection for 72 weeks
But they also should realize this may require them to stay on the drug long term, Aronne said