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RGD selectively binds to integrins, which are cell surface receptors involved in cell-cell and cell-ECM interactions, and are implicated in promoting cancer cell migration and proliferation
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Notwithstanding the encouraging in vitro outcomes for dual-modal imaging via US/MRI, in vivo investigations are requisite to comprehensively ascertain the potential of these nanoparticles in oncological therapy
But the thing is, it doesn't go through your skin, right
This review focuses on the main substrates, inhibitors and reactions played by cytosolic GSTs, with an eye on their relevance for human disease
