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MHRA/EMC SmPCs for Wegovy, Saxenda, Orlistat, and Mounjaro

Importantly, the review also notes that individual responses to incretin-based therapies can vary substantially, and weight regain commonly occurs if treatment is discontinued, highlighting the chronic nature of obesity management

You may also experience mild gastrointestinal symptoms such as nausea, which is common during the first week

Molnar GD, Taylor WF, Ho MM

The strengths are already fixed at mg/mL on the label, and the vial is kept refrigerated

[15] [19] The homeostatic model assessment of insulin resistance (HOMA-IR), a validated surrogate marker calculated from fasting glucose and insulin levels, has shown improvement in patients treated with semaglutide