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Given the comprehensive role of NRF2 in stress response, inflammation, and bone metabolism, we thus hypothesized that NRF2 might be involved in the biological activity of SP
10.1161/01.ATV.0000242794.65541.02 Arterioscler Thromb Vasc Biol
Supernatant was then spun down at 300 g and the pelle t was used for GPX4 activity assay and western blot analysis as detailed in the respective sections
Images were evaluated in real-time to select a cubic volume of interest, 445 cm, centered over the left dorsal putamen at the level of the lentiform nucleus
DNA damage was assessed by measuring the levels of 8-oxo-7,8-dihydroguanine (8-oxoG), representing oxidatively damaged purines ( , the levels of 8-oxoG were reduced by 26.2% compared to baseline and by 35.4% compared to placebo
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