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If a provider

Continuing daily dosing after the body has responded increases side effect risk without meaningful additional benefit

Although previous studies have shown L-carnitine to have cardioprotective effects [47], recent studies have also shown that derivatives of L-carnitine may have adverse consequences on cardiovacular health

Patients begin by scheduling a medical weight loss consultation to discuss weight history, goals, prior treatments, and health concerns

This effect may show some tachyphylaxis (diminishing response) with continued use

That dynamic shifted in 2024, when Wegovy gained an indication for reduced cardiovascular risk in March and Zepbound added an OSA indication in December