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These instructions apply to all lesions regardless of their location (ipsilateral or contralateral) and whether or not they are in the same or different organs/structures

If material is no longer fully dissolved, it is no longer behaving as a proper solution, regardless of what the original COA showed Cloudy Reta is not one mystery with one answer

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This helps prevent these types of issues

27 In general, patients with an irreversible cause should be treated indefinitely, whereas those with a reversible cause should be treated until the deficiency is corrected and symptoms resolve

NICE recommends lifelong intramuscular replacement for vitamin B12 deficiency caused by autoimmune gastritis, or after total gastrectomy or complete terminal ileal resection